From this article you will learn:
- composition analysis,
- detailed instructions for use,
- Solcoseryl gel – reviews, price 2022.
The article was written by a specialist with higher medical education.
Solcoseryl gel is a drug based on deproteinized dialysate from the blood of calves, which accelerates the healing of wounds on the skin and mucous membrane. For example, this drug is widely used in dentistry - to accelerate the healing of erosions and ulcers of the mucous membrane during stomatitis, traumatic injuries to the mucous membrane, and for bedsores under dentures. As for skin wounds, the drug is intended only for the treatment of fresh, wet wounds. To treat wounds and skin damage in the absence of wet discharge, Solcoseryl should be used in the form of an ointment.
The drug is manufactured (Switzerland) and registered as a “medicinal product”. The drug has a high safety profile - in particular, it has no age restrictions, as well as contraindications for use in pregnant and lactating women. When squeezed out of the tube, you can see that the gel is completely transparent, homogeneous and not too liquid (it has a fairly dense consistency). It also has a faint smell of meat broth, which is due to the production technology.
Solcoseryl: photo of packaging
pharmachologic effect
Combined preparation for local use, stimulator of tissue regeneration.
The drug is a chemically and biologically standardized deproteinized dialysate obtained from the blood of healthy dairy calves using the ultrafiltration method. Contains a wide range of natural low-molecular compounds weighing up to 5000 Daltons: glycolipids, nucleosides and nucleotides, amino acids, oligopeptides, trace elements, electrolytes, intermediate products of carbohydrate and fat metabolism. Activates the transport of oxygen and nutrients at the cellular level, increases oxygen consumption by the cell, stimulates ATP synthesis, enhances the proliferation of reversibly damaged cells, especially under hypoxic conditions, thereby accelerating wound healing processes. Stimulates angiogenesis, promotes revascularization of ischemic tissue, as well as creating conditions favorable for collagen synthesis and the growth of fresh granulation tissue, accelerates re-epithelialization and wound closure. The drug also has membrane-stabilizing and cytoprotective effects.
Polidocanol 600 - local anesthetic; acts in the area of peripheral nerve endings, causing their reversible blocking. It has a quick and long-lasting local anesthetic effect. After applying the paste to the oral mucosa, the pain stops within 2-5 minutes; pain relief lasts for 3-5 hours.
Solcoseryl dental adhesive paste forms a protective healing layer on the affected area of the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours, performing the function of a medicinal bandage.
What types are there?
Previously, Solcoseryl was produced only in the form of an ointment, but the manufacturer has significantly expanded its product range:
- Gel. To fix the gel on the mucous membrane, you need to thoroughly treat the desired area with an antimicrobial agent, then wipe it dry with sterile gauze.
- Paste. Perhaps this is the most successful option, ideal for use within the oral cavity. The paste does not spread and holds well; it is often prescribed by dentists for the treatment of gums.
- Ointment. Solcoseryl in ointment form is not used for dental purposes. Due to its too greasy consistency, the product instantly spreads over the gums and is washed off with saliva. This option is most suitable for treating skin.
- Pills. They are used for oral administration for ulcerative lesions of the mucous membrane or for rapid tissue regeneration, for example, after a complex tooth extraction.
Directions for use and dosage
The drug is intended for local use on the oral mucosa.
The affected surface of the mucous membrane must first be dried with a cotton or gauze swab. Apply a strip of paste about 0.5 cm long, without rubbing, onto the mucous membrane in a thin layer with your finger or using a cotton swab, and then lightly moisten the applied paste with water. The procedure is repeated 3-5 times a day after meals and before bedtime. Treatment is carried out until symptoms disappear.
Solcoseryl dental adhesive paste forms a protective therapeutic layer on the affected area of the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours. When applying the paste to undried mucosa, the duration of the therapeutic effect can be reduced.
When treating bedsores from removable dentures, apply the paste to a dry denture and moisten with water.
The recommended course dose of the drug is 1 tube (5 g).
Indications
For dental purposes, this medication is prescribed in the following cases:
- Burns of the mucous membrane.
- Mechanical damage to the gums.
- After tooth extraction.
- Stomatitis.
- Pimples on the gums.
Among the contraindications, the only contraindications can be noted: individual intolerance to the active substances. It is recommended to use only as prescribed by a doctor.
Please note that Solcoseryl is powerless as an independent treatment. The drug does not have antimicrobial properties, so before using the product it is necessary to disinfect the gum area with an antiseptic.
Solcoseryl (gel), 1 pc., 20 g, gel for external use
Solcoseryl injection solution:
IV
or
IM
.
In the treatment of occlusive diseases of peripheral arteries in stages III–IV according to Fontaine
- IV 20 ml daily. Intravenous drip administration in isotonic sodium chloride solution or 5% glucose solution is possible. The duration of therapy is up to 4 weeks and is determined by the clinical picture of the disease.
In the treatment of chronic venous insufficiency accompanied by trophic disorders (Ulcera cruris)
- IV 10 ml 3 times a week. The duration of therapy is no more than 4 weeks and is determined by the clinical picture of the disease. An important additional measure aimed at preventing peripheral “venous” edema is the application of a pressure bandage using an elastic bandage.
In the presence of local trophic tissue disorders, simultaneous therapy with Solcoseryl jelly and then Solcoseryl ointment is recommended.
In the treatment of ischemic and hemorrhagic strokes in severe and extremely severe forms
as the main course - 10 or 20 ml intravenously, respectively, daily for 10 days. Upon completion of the main course - 2 ml intramuscularly or intravenously for 30 days.
Traumatic brain injury (severe brain contusion)
- IV 1000 mg, daily for 5 days.
If intravenous administration of the drug is not possible, the drug can be administered intramuscularly, usually 2 ml per day undiluted.
When using the undiluted drug intravenously, it must be administered slowly, since it is a hypertonic solution.
Solcoseryl gel, ointment:
topically.
Apply directly to the wound surface after preliminary cleansing of the wound using a disinfectant solution.
Before starting treatment of trophic ulcers, as well as in cases of purulent infection of the wound, preliminary surgical treatment is necessary.
Solcoseryl gel is applied to fresh wounds, wounds with wet discharge, and to ulcers with signs of weeping - a thin layer on a cleaned wound 2-3 times a day. It is recommended to lubricate areas where epithelization has begun with Solcoseryl ointment. The use of Solcoseryl gel continues until pronounced granulation tissue forms on the damaged skin surface and the wound dries out.
Solcoseryl ointment is used primarily for the treatment of dry (non-wetting) wounds.
Solcoseryl ointment is applied in a thin layer to a cleaned wound 1-2 times a day; it can be used under bandages. The course of treatment with Solcoseryl ointment continues until the wound is completely healed, its epithelization and the formation of elastic scar tissue.
For the treatment of severe trophic damage to the skin and soft tissues, the simultaneous use of parenteral forms of Solcoseryl is recommended.
Solcoseryl paste (dental, tube 5% 5g)
A country
Switzerland
The country of production may vary depending on the batch of goods. Please check with the operator for detailed information when confirming your order.
Compound
Tube 5 g
Standardized deproteinized dialysate from the blood of healthy dairy calves (in terms of dry matter) - 2.125 mg, polidocanol 600 - 10 mg per 1 g. Excipients: sodium carboxymethylcellulose 22.875 mg, peppermint oil 2.925 mg, menthol 0.075 mg, methyl parahydroxybenzoate (E218) 1.8 mg, propyl parahydroxybenzoate (E216) 0.2 mg, paste base (sodium carboxymethylcellulose, gelatin, pectin, polyethylene 350000, liquid paraffin).
pharmachologic effect
Solcoseryl is a chemically and biologically standardized deproteinized dialysate obtained from the blood of healthy dairy calves by ultrafiltration. Contains a wide range of natural low-molecular compounds weighing up to 5000 Daltons: glycolipids, nucleosides and nucleotides, amino acids, oligopeptides, trace elements, electrolytes, intermediate products of carbohydrate and fat metabolism. Solcoseryl activates the transport of oxygen and nutrients at the cellular level, increases oxygen consumption by the cell, stimulates ATP synthesis, enhances the proliferation of reversibly damaged cells, especially under hypoxic conditions, thereby accelerating wound healing processes. Solcoseryl stimulates angiogenesis, promotes revascularization of ischemic tissue, as well as the creation of conditions favorable for collagen synthesis and the growth of fresh granulation tissue, accelerates re-epithelialization and wound closure. Solcoseryl also has membrane-stabilizing and cytoprotective effects. Polidocanol 600 - local anesthetic; acts in the area of peripheral nerve endings, causing their reversible blocking. It has a quick and long-lasting local anesthetic effect. After applying the paste to the oral mucosa, the pain stops within 2-5 minutes; pain relief lasts for 3-5 hours. Solcoseryl dental adhesive paste forms a protective healing layer on the affected area of the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours, performing the function of a medicinal bandage.
Indications for use
For local use in patients of all age groups to accelerate healing, relieve pain and protect the wound surface in the following diseases and conditions: - gingivitis and periodontal diseases, incl. after surgical interventions, installation of implants, removal of tartar; - bedsores from removable dentures during the period of adaptation to them; - alveolitis; - stomatitis; - lesions of the oral mucosa due to pemphigus; - aphthae; - jams.
Mode of application
The drug is intended for local use on the oral mucosa. The affected surface of the mucous membrane must first be dried with a cotton or gauze swab. Apply a strip of paste about 0.5 cm long, without rubbing, onto the mucous membrane in a thin layer with your finger or using a cotton swab, and then lightly moisten the applied paste with water. The procedure is repeated 3-5 times a day after meals and before bedtime. Treatment is carried out until symptoms disappear. Solcoseryl dental adhesive paste forms a protective therapeutic layer on the affected area of the oral mucosa and protects it from mechanical and chemical damage for 3-5 hours. When applying the paste to undried mucosa, the duration of the therapeutic effect can be reduced. When treating bedsores from removable dentures, apply the paste to a dry denture and moisten with water. The recommended course dose of the drug is 1 tube (5 g).
Interaction
To date, there have been no cases of interaction between Solcoseryl dental adhesive paste and other drugs. When simultaneously prescribing Solcoseryl dental adhesive paste and other drugs in the form of rinses, the paste should be applied after using these drugs.
Side effect
Change in taste sensations. Allergic reactions (local swelling), in the event of which the patient should stop using the drug and consult a doctor.
Contraindications
Individual sensitivity to any of the components of the drug, including free parahydrobenzoic acid (E 210), the presence of a residual amount of which is due to the peculiarities of the technological process during the production of the drug.
Use during pregnancy and lactation There are no contraindications to the use of Solcoseryl dental adhesive paste during pregnancy and lactation (breastfeeding), although special controlled studies on the safety of the drug in women during pregnancy and lactation have not been conducted.
special instructions
You should not put Solcoseryl dental adhesive paste into the wound cavity formed as a result of the removal of molars, wisdom teeth, as well as apicotomy (resection of the apex of the tooth), if the edges of the tooth socket are tightened with subsequent sutures.
Solcoseryl dental adhesive paste does not contain antimicrobial components. In case of acute infection of the affected area of the oral mucosa, which is subject to treatment with this drug, it is necessary to carry out preliminary medical treatment/treatment of the affected area aimed at eliminating the symptoms of inflammation. There are no restrictions regarding the use of the drug in elderly patients. Use in pediatrics There are no restrictions on the use of the drug in children.
