CHOLISAL gel 15g

Nosological classification (ICD-10)

B37.0 Candidal stomatitis
K00.7 Teething syndrome
K05 Gingivitis and periodontal diseases
K12 Stomatitis and related lesions
K13.0 Diseases of the lips
K13.7 Other and unspecified lesions of the oral mucosa
L43.9 Lichen planus, unspecified
L51.9 Erythema multiforme, unspecified
Z100* CLASS XXII Surgical practice
Z97.2 Presence of dental prosthetic device (complete) (partial)

How to use Cholisal gel

The instructions indicate that the ointment is for external use only. It should be applied exclusively to the affected area of the mouth.

The product should be applied 20 minutes before or after meals. You can also rub the ointment in before going to bed. The procedure can be repeated up to 3 times a day. It will be enough for a child to use 0.5 cm, and for an adult – 1 cm.

If a person suffers from periodontal disease, then the ointment can be placed in the gum pockets that appear or effective compresses can be made.

Pharmacodynamics

Choline salicylate has analgesic, anti-inflammatory and antipyretic effects. It inhibits the activity of cyclooxygenase, the functions of macrophages and neutrophils, the production of interleukin-1 and inhibits the synthesis of PG. It also has antimicrobial and antifungal effects (in acidic and alkaline environments).

The analgesic effect appears within 2–3 minutes and lasts 2–8 hours.

Cetalkonium chloride has an antiseptic effect on bacteria, fungi and viruses.

Cholisal does not contain sugar, does not have a local irritating effect and is well tolerated by patients.

Reviews

Regarding the use of the gel during teething, you can find mostly positive reviews. The drug quickly and effectively copes with inflammatory processes, relieves pain and cools the affected area. If you use the product the night before going to bed, its effect will last almost until the morning. It also has an antipyretic effect. For many, it is a plus that the composition does not contain lidocaine, since it can provoke various and severe allergies.

There are also many positive reviews when using ointment for stomatitis. Within 3-5 minutes you can notice a significant improvement in your condition, pain and discomfort disappear. Inflammation disappears 15-20 minutes after application. If you apply compresses before going to bed, you can quickly get rid of the problem and its symptoms.

Indications for the drug Cholisal®

Infectious-inflammatory, ulcerative-necrotic, trophic diseases of the oral mucosa: stomatitis of various etiologies, gingivitis, periodontitis, damage to the mucous membrane when wearing dentures, trauma to the oral mucosa, pain during teething in children, glandular cheilitis, thrush, small surgical interventions, lichen planus, exudative erythema multiforme (including Stevens-Johnson syndrome) - as part of complex therapy.

Adverse reactions and overdose

In rare cases, side effects may occur. A tingling or burning sensation may be felt at the sites where the ointment is applied. This reaction usually disappears after a few minutes. Various allergies may also appear.

No cases of overdose have been identified to date. The gel does not need to be swallowed, only used topically. If there is a lot of ointment on the mucous membrane, then you need to rinse your mouth well. If the composition gets into the gastrointestinal tract, you need to rinse the stomach. Treatment is carried out taking into account the existing symptoms.

Cholisal: composition, release form

Cholisal is a modern dental drug with a pronounced analgesic, anti-inflammatory and antibacterial effect. The gel acquires its unique healing properties thanks to a combination of the following active ingredients:

Anise oil (1.6 mg per 1 g of gel) is a natural oil that has a calming effect on inflammation and kills pathogenic microorganisms;
cetalkonium chloride (87.1 mg per 1 g of gel) – a broad-spectrum antiseptic;
Choline salicylate (100 mcg per 1 g of gel) is an analgesic that also relieves inflammation.

Auxiliary components: 50 mg of glycerin, up to 1 g of water, 390 mg of ethyl alcohol, 20 mg of hyaetellose, 1.5 mg of methyloxybenzoate, 0.8 mg of propyl parahydroxybenzoate.

Why is this composition so good?

When most dental preparations that are used topically differ only in their superficial effect, Cholisal gel penetrates into the deep layers of the oral mucosa. This property is given to the gel by the active substance choline salicylate. The component formed from salicylic acid acts on the site of inflammation, blocking inflammatory mediators in the oral mucosa. The analgesic component has a light structure, so it penetrates quite deeply into the layers of the mucous membrane.

Cholisal gel acts simultaneously on bacteria, fungi and viruses; this universal property is given to it by a broad-spectrum antiseptic - cetalkonium chloride.

The product is available in gel form, 10 g in aluminum tubes, sealed cardboard packs.

Cholisal or Asepta

Manufacturer: Vertex, Russia
Release form: gel

Active ingredient: Metronidazole, Chlorhexidine bigluconate

Synonyms: Albadent, Metrogil Denta

Asepta is a cheaper analogue of Cholisal for adults. Both gels are used to relieve inflammation in gum disease. In addition to the anti-inflammatory effect, it has an analgesic and antimicrobial effect. Asepta is not prescribed in the acute stage of periodontal disease; with such a diagnosis, it is used exclusively for prevention.

For a full therapeutic effect, the Asept analogue is used for 10 days, 3 times a day. No side effects were found on the body of pregnant and lactating women.

There is Asepta gel with propolis. Its only drawback is an allergic reaction to bee products. If a patient is allergic to this group of components, Cholisal is prescribed.

Cholisal or Solcoseryl - which is better

Manufacturer: LEGACY PHARMACEUTICALS SWITZERLAND, Switzerland
Release form: gel, ointment, paste

Active ingredient: deproteinized dialysate, polidocanol

Synonyms: Vitadent, Dicloran, Denta gel, Stomatofit

If we compare the effectiveness of using medications to treat diseases of the gums and mucous membranes in adult patients, then both medications are equal. Customer reviews report rapid therapeutic results when using two drugs. To eliminate ulcerations on the mucous membranes of the lips and cheeks, both drugs will cope in 3-4 days.

The pediatrician decides which drug to choose for the child. Both products can cause allergic skin rashes. Solcoseryl distorts the taste while eating, this is due to the fact that the analogue affects the functioning of taste buds. Cholisal gives a characteristic taste of anise, which can also be a reason for refusing to eat.

Holisal: reviews from specialists and patients

What can you say about Holisal?

Only good. All specialists from the dental industry speak only positively about the drug. Negative reviews are extremely rare, and, as a rule, they are from patients who made mistakes in trying to self-medicate. For example, some patients begin to use the product without first consulting a dentist, completely forgetting that inflammation in the mouth always has a cause. In such cases, using Cholisal alone is not enough, since the treatment will be ineffective and short-term. Therefore, it is necessary to discover the cause and carry out full therapy to avoid relapse of the disease.

What benefits do doctors and patients notice?

Versatility of use. Cholisal is available in one form, which allows it to be used by both adults and children. There are no age restrictions, the gel is safe and effective for everyone.
In normal doses, the drug is inert and does not react with other drugs, which makes it possible to include it in combination therapy.
No risk of overdose.
No sugar in the composition.
The drug penetrates deeply into tissues, providing a stronger and longer-lasting therapeutic effect.
Quickly relieves pain.
Cholisal gel does not affect the psychomotor state of the patient, so it can be used while driving a vehicle or when working with complex mechanisms.
The gel is applied topically, which eliminates a number of side effects that can usually occur with oral medications.
Availability and popularity. Cholisal is sold without a prescription, so you can easily purchase it at any pharmacy.

special instructions

Despite the many advantages and high safety of the drug, dentists all recommend adhering to several rules:

Gel in large doses can enhance the effect of antipyretics, analgesics and anti-inflammatory drugs, so it is especially important to monitor the dose of the gel used if you take such drugs.
Women during lactation and pregnancy, as well as children under 1 year of age, are advised to use the gel with caution.

Cholisal Dental or Cholisal gel – which is better, what’s the difference

Manufacturer: PHARMACEUTICAL WORKS JELFA, Poland
Release form: gel

Active ingredient: atropine, aprotinin, propylene glycol, peppermint oil

Synonyms: Cholisal, sage leaves, Fitosept

Cholisal Dental does not contain NSAIDs and antiseptics, unlike Cholisal gel. This is a cosmetic product, the drug is used for preventive purposes from the age of 14. The Dental form prevents unpleasant odor and the development of inflammation when wearing dentures and braces. Structures in the mouth can create difficult to reach areas for cleaning. Food gets into them and bacteria spread.

Holisal Dental is used daily 2 to 4 times a day. After brushing your teeth, apply with a special applicator, which comes complete with the gel.

Unlike Cholisal gel, the drug is not used when teething.

Cholisal or Metrogyl Denta - which is better and more effective, what is the difference

Manufacturer: UNIQUE PHARMACEUTICAL Laboratories, India
Release form: gel

Active ingredient: metronidazole, chlorhexidine

Synonyms: Romazulan, Metrodent, Dentamet, Rotocan

Metrolil Denta is an analogue of Cholisal ointment, used from 6 years of age. Both drugs are suitable for relieving inflammation. It is important to consider that Metrogyl Denta does not relieve pain.

The advantage of Cholisal is that the drug is used in children from 1 year of age and has a broader effect in treating the disease. Metrolil gel not only kills bacterial colonies, but also destroys viruses and fungi. The medication acts specifically against inflammation, alleviates the period of illness, and accelerates recovery.

Comments

Are there any other gels on sale besides Cholisal that you would recommend for teething?

Alena (02.10.2019 at 10:14) Reply to comment

Editorial staff of the portal UltraSmile.ru (04.10.2019 at 09:24) Reply to comment

Tell me, can Cholisal gel be used for a six-month-old baby who has started teething? The fact is that the child is very restless due to teething and I would like to help him somehow.

Vika (10/14/2019 at 6:07 pm) Reply to comment

How often can you use Cholisal gel for children under one year old whose first teeth have just begun to emerge? Is there any dosage and can this gel be used at night?

Elena (10/14/2019 at 6:15 pm) Reply to comment

The child just turned 5 months old and his teeth began to come out. Became restless and refuses to eat, we heard that Cholisal gel can help cope with problems such as pain and swelling of the gums. How often should a five month old baby use it?

Alisa (10/14/2019 at 6:17 pm) Reply to comment

Can Cholisal gel cause an allergic reaction in a child? It should be used correctly initially, in order to observe the baby’s reaction, the teeth are being cut, but I would also like to avoid the consequences.

Masha Archipenko (10/14/2019 at 6:19 pm) Reply to comment

Please tell me whether Cholisal gel will harm the child’s health? Why am I asking, because it contains chemical components... what effect do they have on the child’s body?

Anna (11/02/2019 at 12:44 pm) Reply to comment

How long can a child use Cholisal gel? During the examination, the doctor said that the upper two teeth were about to erupt, and the lower ones right behind them. Perhaps, immediately after these ones erupt, others will begin to erupt. My daughter is already acting restless, but if I start using Cholisal now, won’t it turn out that at the very peak of the pain I will have to stop using it?

Daria (11/11/2019 at 12:19 pm) Reply to comment

Today I purchased Cholisal, but have not used it yet. Tell me where is the best place to store this product after opening so that it does not lose its properties in the future? Thank you in advance for your answer.

Zhanna (11.11.2019 at 16:52) Reply to comment

I recently had my wisdom teeth cut out. I was periodically very sick, I made an appointment with the dentist, but I still have to live to see the dentist! A friend gave me this same Cholisal, if it helps children, then why don’t I try it, we are all children at heart. The pain was relieved. I would like to know for the future, since I have another tooth about to come out, what good analogues are there for adults?

Alice (11/11/2019 at 07:46 pm) Reply to comment

Cholisal helps not only children, but also adults with stomatitis. It stings slightly when you apply it to your gums. Can you recommend an analogue of this gel? Otherwise, it works fine for children, but for adults it is sometimes weak.

Nata (11/27/2019 at 10:42 pm) Reply to comment

How long does Cholisal last and how often can it be used? I didn’t use anything at all with my first child, the second one is very restless, there is no peaceful life without the gel!

Anna (11/28/2019 at 12:06 pm) Reply to comment

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Comparison with other drugs

As we can see, the choice of drugs for the treatment of the oral mucosa is considerable, but all these drugs have mainly a superficial and narrow therapeutic effect. For example, today there is a large selection of dental drugs that have only an antibacterial effect. Such products most often include antibiotics and antiseptic components (chlorhexidine, metronidazole). Such drugs include Asepta-balsam, Metrogyl Denta, Faringosept and others.

There are also dental products on the market that have only an anti-inflammatory effect (for example, “Parodontocide”) or an analgesic effect (for example, “Kamistad”, “Dentol”).

Therefore, we can say that the composition of Cholisal is unique in its kind. It simultaneously has anti-inflammatory, antibacterial, antimycotic and analgesic effects, which most other dental products cannot boast of.

Diagnosis of candidiasis

If the listed symptoms of candidiasis appear, you should contact your dentist for an examination. Only a doctor can make a correct diagnosis, determine the cause of the disease and prescribe comprehensive treatment for oral thrush in adults. As part of the examination, a detailed medical history is collected, mucosal scrapings are made, and a clinical blood test is performed. The diagnosis can be confirmed by microscopic examination of a scraping, in which a pathogenic fungus can be detected. After receiving all the results, an individual treatment plan is drawn up.

pharmachologic effect

Manufacturer: PHARMACEUTICAL WORKS JELFA, Poland
Release form: gel

Active ingredient: choline salicylate, cetalkonium chloride

Synonyms: Metrodent, Dentamet, Rotokan

Cholisal is used to treat diseases of the oral cavity. When applied, the gel is quickly absorbed and spreads inside the affected tissues. Cholisal eliminates bleeding gums and bad breath, relieves pain and relieves inflammation, reduces the number of pathogenic bacteria, and acts against fungal infections.

The adhesive base increases the effectiveness of the drug and retains the active ingredients on the surface for up to 6 hours. The gel relieves pain in 2 minutes.

Cheaper analogues of the drug Cholisal produced in Russia

At the moment, in pharmacies you can purchase not only imported original dental gels, but also their inexpensive Russian-made analogues. They also have anti-inflammatory and antiseptic properties, but differ in composition.

Asepta

Pharmaceutical (Russia) produces a range of products for the treatment and prevention of oral diseases. As an analogue of Cholisal, Asepta can be used in the following forms:

Adhesive balm for gums. Contains a combination of antimicrobial substances - chorhexidine and metronidazole. Thanks to their combined action, this balm helps eliminate most pathogenic pathogens: dermatophytes, yeast, protozoa, anaerobic bacteria.
The balm also contains menthol and mint essential oil, which have anti-inflammatory properties, relieve pain, and eliminate swelling of the gums. The drug has an adhesive base, which provides a long-lasting effect and promotes a speedy recovery.
Asepta series drugs
Gel with propolis. It has a complex effect, helps to quickly get rid of pain, and activates the regenerative properties of damaged tissues. Most gram-positive bacteria are sensitive to propolis. Thanks to the gel base, rapid penetration of the active component into the affected area is ensured.

To achieve the fastest possible effect, the use of local forms of Asepta in the form of gel and balm should be accompanied by a set of hygiene procedures. To do this, use toothpastes and rinses from the Asepta Plus and Asepta Parodontal series. To strengthen the health of teeth and gums from within the body, the manufacturer has developed a special vitamin and mineral complex based on coral calcium, coenzyme Q10, vitamins (ascorbic acid, nicotinamide, vitamin B3, D3, retinol) and green tea extract.

Dentamet

According to the anatomical and therapeutic classification, Dentamet dental gel belongs to the group “Antiseptics and antimicrobials for local treatment of inflammatory diseases of the oral mucosa.” The medicine has a pronounced disinfectant effect due to the presence of two active substances - metronidazole and chlorhexidine.

The base used in the production of this gel is glycerol, water, propylene glycol, arepol, sucrose, triethanolamine, and menthol.

Manufacturer – pharmaceutical, Russia. Sold in aluminum tubes containing 10 or 25 g of colorless gel. The drug has a homogeneous structure, a white or yellowish tint is allowed, and a specific odor. When applied to the mucous membrane, a sweetish taste and coldness are felt at the site of application.

Dentamet is prescribed for the treatment and prevention of oral inflammation caused by the following microorganisms:

Porphyromonas gingivalis;
prevotella;
borrelia;
viruses;
yeast;
dermatophytes.

If you have hypersensitivity to one of the components, the drug should not be used. It is not recommended to use Dentamet during pregnancy and lactation; however, according to indications, it can be prescribed after 14 weeks. Age limit – 6 years.

This gel is intended for topical use. Usually apply a 5-10 mm strip of gel to the affected area and rub in with massaging movements. Manipulations are performed after meals and hygiene procedures 3-4 times a day.

Periodonticide

Under this trade name it produces a series of medicines for the treatment of inflammation of the oral cavity of various origins. All of them are plant-based and contain the following active ingredients:

phenyl salicylate - an ester of salicylic acid, which has a pronounced anti-inflammatory effect and causes the death of most bacteria;
Eugenol is an aromatic substance obtained from clove extract. Helps give fresh breath and creates a protective layer on the mucous membrane;
thymol is an antiseptic, has an antipruritic effect;
sodium fluoride – protects against caries and normalizes enamel mineralization;
allantoin is a derivative of uric acid, has astringent properties;
extracts of cloves, oregano, mint, sage.

The drugs are indicated for the treatment of gingivitis, stomatitis, periodontitis and periodontal disease. Can be used when wearing braces and dentures.

Series of products Periodontocide

The Parodontocid product line includes:

The gel (15 g tube) is evenly applied to the affected areas and does not disturb the natural microflora. Used in the form of applications 2-3 times a day for a week.
The solution in bottles (25 and 50 ml) is used for rinsing the mouth after brushing the teeth and for massaging the gums. Requires dilution in water.
Spray (25 ml bottle) is used to irrigate teeth and surrounding tissues.
Rinse aid (ready solution) can be used for preventive purposes.
Toothpaste (50 ml) is used to prevent periodontitis.

Periodontocide can be used during pregnancy and lactation, as well as in children over 7 years of age. When using these drugs, allergic reactions may occur. No side effects were recorded. Periodontocide does not cause darkening of enamel and polymer fillings.

Cholisal or Kalgel - which is better for teething and stomatitis

Manufacturer: GlaxoSmithKline Pharmaceuticals, Poland
Release form: gel

Active ingredient: lidocaine, cetylpyridinium chloride

Synonyms: Eucalyptus tincture, Rotocan, Tantum Verde

Kalgel is a substitute for Cholisal gel for gums. Both drugs are used when baby teeth appear. The cost of gels is at the same level. When choosing between two medications, it would be preferable to buy Kalgel, since its use is allowed from 3 months, and Cholisal - from 12 months.

Contraindications are allergies to lidocaine and severe stages of heart disease. Because of this, one drop of Kalgel is applied for the first time to make sure that the child is not intolerant to the component. For adults and children over one year of age, when gums are inflamed or an infection is attached to the mucous membrane, it is better to use Cholisal, it is more effective in fighting microbes.

How does thrush develop?

At the initial stage, the fungus penetrates the cells, where it begins to multiply and secrete enzymes that irritate the mucous membrane and dissolve surrounding tissues. In this regard, candidiasis causes swelling, redness, increased sensitivity, a feeling of dryness and soreness in the mouth. As the disease develops, a white cheesy coating forms on the mucosa, consisting of destroyed epithelial cells, fibrin, keratin, food debris and bacteria. At the initial stage, candidiasis in adults looks like small white grains, which subsequently increase in number and size. As the disease progresses, plaque turns into large plaques or a milky film. In the absence of timely treatment for thrush in the mouth, the affected areas begin to merge with each other, covering the inner surface of the cheeks and lips, gums, tongue, palate, and tonsils.

Causes of candidiasis in the mouth

Candidiasis in the mouth most often affects children, especially infants. In adults, thrush is much less common. People over 60 years of age are at risk, especially those who wear dentures, as well as people suffering from various diseases that cause decreased immunity. Among the factors contributing to the development of candidiasis in adults are:

immunodeficiency states;
pregnancy (the causes of thrush are metabolic disorders, changes in hormonal levels, decreased immunity);
diabetes mellitus, HIV, tuberculosis and other serious diseases;
prolonged or uncontrolled use of antibiotics and other medications that reduce the body's defenses;
dysbacteriosis and other gastrointestinal diseases;
lack of vitamins B, C and PP;
radiation and chemotherapy;
bad habits (alcoholism, drug addiction);
injuries to the oral mucosa due to malocclusion or incorrectly selected implants, dentures or braces.

In addition to the fact that Candida bacteria are present in the human body, thrush can also be contracted from another carrier, for example, through sexual contact, a kiss, through a toothbrush or shared utensils.