Nimesil granules d/susp. for oral administration 100 mg pack 2g N9 buy in Yeisk, price from 409.00 rub. 88 pharmacies in Yeysk

Release forms and dosages

The drug is produced in granules, from which a suspension is prepared for oral administration. The granules are placed in sealed bags of 2 g. You can buy Nimesil in packages of 9, 15, 30 sachets. The drug is prescribed only to adults. For elderly people, the dosage is selected individually based on the severity of the disease and the effectiveness of the drug. Take the medicine only after meals.

Composition and active substance

The main active ingredient of Nimesil is Nimesulide. One two-gram sachet of the drug contains one hundred milligrams of the active substance. Nimesulide is supplemented with other components - sucrose, ketomacrogol, anhydrous citric acid, maltodextrin and orange flavor.

Indications

Nimesil is prescribed to reduce pain and inflammation during the treatment of the following diseases and symptoms:

acute muscle and musculoskeletal pain;
toothache;
pain during the treatment of osteoarthritis;
dysalgomenorrhea.

In addition, the drug is actively used as an antipyretic for the treatment of acute respiratory viral infections and colds of varying degrees of complexity.

Effect on the body

The drug easily overcomes histohematic barriers and is absorbed from the gastrointestinal tract within 2-3 hours after administration. About half of the drug taken is eliminated by the kidneys. Experimental studies involving patients with clinically confirmed renal failure and healthy volunteers showed that the concentration of nimesulide was within the acceptable range. However, only patients with mild and moderate stages of renal failure were allowed to participate in the study. The next time Nimesil was used, no accumulation of the active substance in the body was detected.

For what diseases do you need to take nimesil?

The drug is used as prescribed by a doctor as a “second-line” medication and is added to therapy additionally when other drugs fail to relieve an attack of pain and relieve symptoms of inflammation that are caused by:

toothache;
painful menstruation and inflammation of the genital organs in women and men;
damage to joints and ligaments that occur due to injuries, dislocations, fractures, sprains;
pain in the spine and back;
degenerative changes in joints with osteoarthritis.

Contraindications

Nimesil is contraindicated in the following cases:

children under 12 years of age;
pregnancy and lactation;
alcohol and drug addiction;
high sensitivity of the body to the drug or components included in the drug;
hyperergic and hepatotoxic reactions;
simultaneous use of Nimesil and drugs with potential hepatotoxicity;
any inflammatory processes of the gastrointestinal tract, perforation, peptic ulcer, bleeding;
after undergoing coronary artery bypass surgery;
febrile attacks and high temperature during ARVI;
bronchial asthma, recurrent polyposis of the nose and sinuses, accompanied by intolerance to NSAIDs;
the presence of hemorrhages and bleeding, as well as the presence of diseases accompanied by them;
if you have problems with blood clotting;
acute heart, liver and kidney failure.

Compatibility with other drugs

The use of Nimesil with other drugs from the glucorticosteroid group, as well as with antiplatelet inhibitors, selective inhibitors can cause bleeding and provoke the formation of ulcerative inflammation in the gastrointestinal tract. It is also possible to increase anticoagulants, which will provoke the same consequences. If treatment without the use of Nimesil and the listed drugs is unavoidable, it is important to carefully monitor the intake.

When taken simultaneously with diuretics, the components of Nimesil can weaken the effect of the latter by reducing the excretion of sodium and potassium from the body. That is why the use of the drug is not recommended for people with heart and kidney problems. The effect of antihypertensive drugs can also be reduced when taken simultaneously with Nimesil.

Blood pressure medications are also combined with Nimesil with extreme caution. This is especially true for elderly patients. It is important to monitor proper kidney function while taking the drug and regularly drink enough fluids.

The drug can reduce the clearance of lithium. As a result, the concentration and toxicity of the element in the blood plasma increases significantly. If the patient is forced to simultaneously take lithium preparations and Nimesil, it is necessary to strictly monitor lithium levels in the blood plasma.

There was no interaction between Nimesil and antacid drugs, as well as digoxin, theophylline, and cimetidine.

During the research, it was possible to establish that Nimesil can be displaced by salicylic and valproic acids from the sites of their binding to each other. However, this relationship does not affect the overall effect of taking these drugs together.

Overdose

Signs of overdose:

vomit;
drowsiness;
apathy;
nausea;
epigastric pain.

The development of gastrointestinal bleeding is possible. In especially rare cases, there is a possibility of increased blood pressure, acute kidney failure, respiratory depression, anaphylactoid reactions , and coma .

Treatment of overdose is symptomatic. There is no selective antidote. If no more than 4 hours have passed since the overdose, it is necessary to rinse the stomach and take enterosorbents, for which activated carbon or an osmotic laxative is used. Monitoring the functioning of the kidneys and liver is indicated.

How to take Nimesil

Usually a twice daily dose is prescribed. A single dose is equal to one sachet of Nimesil. The drug dissolves in about one hundred milliliters of warm water. The suspension is drunk all at once after meals. The prepared solution cannot be stored and consumed after some time. Based on the results of monitoring the effectiveness of treatment and the severity of the patient’s condition, the dose may be increased.

Nimesil and pregnancy

Nimesil is not prescribed during pregnancy or lactation; it is contraindicated for a number of reasons. The drug provokes pregnancy complications and significantly inhibits the development of the fetus. Even small doses of Nimesil can lead to miscarriage and abnormal development of the fetus with serious consequences for the future health of the mother.

Nimesil and childhood

The drug is also contraindicated for children under 12 years of age. After 12 years, Nimesil is prescribed in the same dosage as for adults.

Nimesil in the elderly

Nimesil is prescribed to elderly patients with extreme caution. This category of patients is more susceptible than others to side effects from taking medications. In addition, older patients often already have a number of serious diseases, and taking the drug can only worsen the condition. Therefore, Nimesil is prescribed to older people in individual dosages. The treatment takes place under the strict supervision of a doctor.

Nimesil and chronic diseases

In the presence of a number of chronic diseases (heart, liver and kidney diseases), Nimesil is contraindicated. In other cases, in the presence of chronic diseases and the need to take the drug, treatment also takes place under the strict supervision of a doctor and regular laboratory tests of blood parameters and others. Nimesil is regularly prescribed for chronic rheumatic diseases.

Nimesil is one of the most effective medicines today. In addition to a pronounced analgesic effect, the drug is actively used for colds and ARVI as an antipyretic. Plus, clinical studies have found that even with an impressive list of contraindications, Nimesil is easier to tolerate, and the risk of side effects is much lower than other non-steroidal anti-inflammatory drugs.

Possible adverse reactions to Nimesil and overdose

Non-standard effects during treatment appear:

allergies - with increased sweating, rashes, itching, erythema, urticaria, dermatitis, Lyell and Stevens-Johnson syndrome, Quincke's edema;
problems with the hematopoietic system - anemic conditions, insufficient levels of platelets, leukocytes, red blood cells, hemorrhagic syndrome, thrombocytopenic purpura, increased number of eosinophils;
visual and nervous disorders - panic attacks, vestibular dysfunction, cephalalgia, poor sleep with nightmares, non-inflammatory brain damage, unreasonable anxiety, drowsiness, decreased visual acuity;
dysfunction of the circulatory system - rapid heartbeat, arterial hypertension, hot flashes, changes in blood pressure;
pathologies of the digestive tract - dyspeptic disorders, gastritis, increased gas formation, painful sensations in the epigastric region, ulcers and perforation of the gastrointestinal tract, hepatitis, icteric discoloration of the skin, an increase in the number of liver enzymes.

When adverse reactions occur in the respiratory department, shortness of breath is observed. In other cases, there is a decrease in body temperature, hematuria, problems with urination, and asthenic syndrome.

Symptoms of an overdose of Nimesil include vomiting, apathy, nausea and drowsiness. In difficult cases, spontaneous bleeding develops in the gastrointestinal tract, sometimes there is an increase in blood pressure, acute kidney dysfunction, breathing problems, anaphylaxis, and coma.

To relieve the clinical manifestations of an overdose, symptomatic treatment is used, with gastric lavage, taking activated charcoal (1 tablet per 10 kg of weight), and an osmotic laxative. It is imperative to monitor the functionality of the liver and kidneys.

Is it possible to do x-rays?

Contrary to popular belief, X-rays can be taken during pregnancy. For this purpose, computer radiovisiographs are used. The radiation dose received by the patient when using a visiograph is minimal. If possible, the study should be carried out in the 2nd trimester

, excluding cases where urgent help is required - severe, acute pain in the teeth during pregnancy. X-ray examination is carried out observing all possible means of protecting the fetus.

“Fighting” radiation on the visiograph, women calmly fly south to eat fruit and bask in the sun. Not knowing that during a 2-3 hour flight a person receives 20-30 μSv. This is a radiation dose equivalent to 10-15 images on a visiograph. Ionizing radiation differs from light rays only in wavelength and has a damaging effect only under certain conditions.

How to relieve pain yourself

Rinsing with a soda solution (1 teaspoon of soda per glass of warm water) will help temporarily relieve toothache during pregnancy. You need to rinse your mouth more often, every 2 hours. In addition to soda, you can use Furacilin solution, decoctions of medicinal herbs - chamomile, oak bark, yarrow.

Not recommended

use herbs containing essential oils (sage, eucalyptus, peppermint, cloves, etc.), they can cause severe uterine cramps.

Severe dental pain during pregnancy can be treated with a suitable anesthetic. Steroid-based drugs and drugs that penetrate the placental barrier are contraindicated.

Enlargement of wisdom teeth

The growth of wisdom teeth is associated with various pathological processes and pain. Nimesil is used to block them. The product has a preventive effect, reducing the risk of attachment of viral flora. The dose is prescribed by a medical specialist in accordance with the clinical picture.

Symptoms of gingivitis are inflammation of the gums. In this case, you can note blood circulation, pain, swelling and overflow of blood vessels. The effective action of Nimesil makes it possible to use it to eliminate the clinical picture.